Choice of plant for the production of plant-based vaccine determines the route of administration of the vaccine, since some plants and its products cannot be consumed directly. Thus the development of plant-based vaccines have to take into account the heat or pressure treatments. Cereal crops are one of the most attractive type of plant for the production of plant-based vaccines since the vaccine produced in seeds are most stable over long storage periods.
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Currently the only plant-based vaccine approved is that for Newcastle disease vaccine for poultry. Although, plant-based vaccines are not quite ready for humans in the primetime, there are a number of clinical trials ongoing. Research in plant-based vaccine for influenza has seen some success in the past few years probably because the haemagglutinin (HA) protein can be well expressed in plants and can undergo proper post translational folding.
Plant-based vaccines have several advantages including cheap and large scale production, readily accepted by patients and stable for long term storage of the antigen. Plant-based vaccines could be one of the best methods for reducing the burden of infectious diseases globally.
Additionally, unlike traditional vaccines, plant-based vaccines contamination with plant virus would have a negligible likelihood of adverse effect on humans. The positives of plant-based vaccines are outweighed by the negative factors such as allergic reactions, and risk of escaping the lab resulting in unforeseen consequences that may hinder the approval and growth of the plant-based vaccines market.
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Market Segmentation:
Based on the vaccine type |
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Based on the plant type |
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Based on the application |
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