Biomarkers are biological markers which measure the biological states. It is used for indicating the normal biological and pathogenic process to a therapeutic intervention. These biomarkers can also be used in combination to access disease state of an individual. Scientists are exploring more about the structural and functional differences of the neurological diseases. Moreover, there has been an increase in biobanks which have help address unmet needs in oncology, neuroscience, and cardiovascular disease.
The University of British Columbia and the Karolinska Institute in Sweden have set up biobanks that provide necessary resources and information for biomedical research. Alzheimer’s is the most common form of dementia affecting 12 million people. Neuroimaging and neuropsychological probes can help predict Alzheimer before behavioral tests diagnose. Thus pre-assessment tests such as Positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) are driving the demand for neurological biomarkers.
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Market Segmentation:
On the basis of imaging techniques
- Transcranial magnetic stimulation (TMS)
- Diffusion tensor imaging (DTI)
- Conventional structural MRI (sMRI)
- Functional magnetic resonance imaging (fMRI)
- Positron emission tomography (PET)
On the basis of application
- Proteomics based biomarkers
- Genomic based biomarkers
- Imaging based biomarkers
- Metabolic based biomarkers
On the basis of indication
- Alzheimer’s disease (AD)
- Multiple sclerosis (MS)
- Parkinson’s disease (PD)
- Autism spectrum disorder (ASD)
On the basis of end-user
- Hospitals
- Clinics
- Diagnostic and research laboratories
On the basis of services
- Sample preparation
- Assay development
- Biomarker validation and testing
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In terms of geography, the global neurological biomarkers market has been divided into five regions including North- America, Asia- Pacific and Middle-East & Africa, Latin America and Europe. North America has a major revenue share in the neurological biomarkers industry as many prominent market players are present in this region, the number of R&D projects carried out and the government funding received by academic universities to undertake research.
For instance in August 2015, researchers, patients and various non-profit organizations participated in the Imaging Dementia — Evidence for Amyloid Scanning (IDEAS) study. The USD 100 million project aims to study the utility of amyloid PET imaging to diagnose dementia, Alzheimer’s and cognitive impairment.
Asia-Pacific is the fastest growing region as the region offers huge population base, high incidence rate of neurological abnormalities, entry of new market players and huge aging population. In developing economies such as India and China, new industry players are trying to establish their market presence by developing the generic version of the biomarker, through contract research organizations. This has further helped in reducing the manufacturing cost for the company and other production-related costs.
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Key players in the neurological biomarkers industry are Myriad RBM, Proteome Sciences, QIAGEN, Thermo Fisher Scientific, AbaStar MDx, Acumen Pharmaceuticals, Abiant, Aepodia, Athena Diagnostics, ImmunArray, Quanterix and Cisbio Bioassays.
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