The 5HT3 Receptor Antagonists Market is all set to witness staggering growth in the upcoming period. With technological advancements under its belt, the healthcare vertical is witnessing hi-tech demands. In other words, the healthcare personnel is expected to be abreast with the operations of high-tech devices like handheld computers, smart infusion pumps, and so on. Also, utmost care needs to be taken concerning scanning right the very first time along with vibration alert to not disturb the sleeping patients.
5-hydroxytryptamine receptor antagonists (5-HT3 RAs) are a group of drugs, used to control nausea and vomiting. The effectiveness of these drugs has revolutionized the management of nausea and vomiting, especially in the treatment of nausea and vomiting after surgery and in individuals undergoing chemotherapy or radiation therapy.
By 2040, the annual number of cancer cases is expected to increase to 29.5 million. The increased prevalence of cancer is to explode new cases of nausea and vomiting and promote the 5HT3 receptor antagonists market. Increase in usage of chemotherapeutic agents due to increasing incidence of cancers is the major growth driver of 5HT3 receptor antagonists treatment market.
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In addition, the demand for these drugs is increasing during the forecast period as the application of these drugs increases in post-surgical surgical procedures for the prevention and treatment of nausea and vomiting. In addition, the approval of new drugs for the treatment of acute and severe CINV, RINV and postoperative induced nausea and vomiting provides an important opportunity for global players operating in this market.
Increased R & D investment by pharmaceutical and biotechnology companies for highly effective and efficient drug development with minimized side effects is expected to increase demand for 5HT3 receptor antagonists during the forecast period.
Taiho Pharmaceutical Co., Ltd. (April 22, 2010) announced the release of Aloxi IV Injection® (palonosetron hydrochloride), the 5-HT3 (serotonin) receptor antagonist antiemetic agent. Aloxi® was developed by Taiho Pharmaceuticals for Japanese market on a licensed agreement between Taiho and Helsinn of Switzerland in 2004.
SANCUSO (Kyowa Kirin, Inc.) is the first and only prescription patch approved for CINV prevention, providing a way to prevent chemotherapy nausea and vomiting instead of taking medications.
Heron Therapeutics, Inc. on August 10, 2016, announced that the U.S. Food and Drug Administration (FDA) had approved sustained release guranisetorone injection (SUSTOL®), a serotonin 3 (5HT3) receptor antagonist.
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Helsinn Group announced AKYNZEO® injection, a new liquid IV solution in the US in 2020. Rise in incidence of cancer in U.S., increase in access to health care facilities for chemotherapy and radiation therapy, and surge in disposable income make U.S. the fastest growing market for 5HT3 receptors antagonists drugs during the forecast period.
Helsinn announces European approval of the IV formulation of AKYNZEO® (fosnetupitant / palonosetron). Europe is projected to dominate the global market owing to high prevalence and incidence of cancer.
- TAIHO PHARMACEUTICAL CO. LTD.
- MedKoo Biosciences Inc.
- Cipla Inc.
- Helsinn Healthcare SA
- Sanofi
- F. Hoffmann-La Roche Ltd
- MEDNAX Services
- Kyowa Kirin Inc.
- Heron Therapeutics Inc.
- GlaxoSmithKline plc.
- Fortovia Therapeutics Inc.
Pediatrx Launches Granisoltm, the Only FDA-Approved, Ready-To-Use Oral Liquid Solution of Granisetron in 2010.
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Key Segments
By Product Type
- First-Generation Serotonin Blockers
- Second-Generation Serotonin Blockers
By Applications
- Chemotherapy-Induced Nausea And Vomiting (CINV)
- Radiation-Induced Nausea And Vomiting (RINV)
- Post-Operative Nausea And Vomiting (PONV)
By Route of Administration
- Intravenous
- Topical Patches
- Oral
By Distribution Channel
- Hospital Pharmacy
- Drugstore
- Online Pharmacy
- Retail Pharmacy
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