Microscopic examination of tissue samples is often prescribed by doctors today to understand what disease the tissue is affected by and to diagnose and determine the severity and progression of the disease. A clear understanding of the normal structure of a tissue sample is essential to interpret the changes that occur in a tissue sample during disease progression.
Some diseased tissues are very difficult to evaluate and require careful dissection. Therefore, microtome instruments are used to cut biological specimens into uniformly thin sections for detailed microscopy. There has been a gradual shift towards automation in histology in recent years.
The high demand for microtome in pathology, histopathology, textile and other industries will increase the demand for automation to reduce manpower. Sectioning using an automated microtome enables faster capabilities for the study and analysis of light microscopy histology, spectroscopy, electron microscopy, and plant microscopy. Various cutting mode operations such as single, interval, multiple and continuous provided high-throughput serial cutting.
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Automated microtome based products subdivided into rotating, vibrating blades, lasers, saws and ultra microtomes and cryogenic microtomes. Rotary microtomes are commonly used because they are heavy and do not vibrate when cutting. Rotational microtomes operate in a stepwise rotational motion where the cut is part of the rotational motion. The knife is fixed on an auto-rotating microtome.
Autorotating microtomes can be operated automatically, semi-automatically, and manually, but there is a high demand for autorotating microtomes today. Automated rotating microtome significantly improves ergonomics by reducing repetitive stress on joints. Provides accurate, consistent, high-quality sectioning and preserves tissue.
The rotary microtome segment holds a large share of the automated microtome market owing to the growing number of histopathology laboratories, increasing awareness of digital pathology systems and high growth of anatomical pathology laboratories in emerging economies.
The growing growth of histological procedures is in turn a key factor that is expected to accelerate the automated microtome market. Rising awareness of early diagnosis of chronic diseases and growing demand for advanced diagnostic equipment are major factors driving the growth of the global automated microtome market.
The growing number of geriatric populations worldwide and rising medical costs are also propelling the growth of the automated microtome market. The growing number of histopathology laboratories and increasing adoption of automated devices are expected to provide growth opportunities in emerging markets. Hospital consolidation and reimbursement cuts are some of the factors hindering the growth of the automated microtome market.
Different blades are used to cut different types of specimens for detailed examination of tissue samples. For cutting very thin sections, automated microtomes use special glass, metal or diamond blades, depending on the type of specimen and the desired thickness. Glass blades used in sample preparation activities for light and electron microscopy applications.
Diamond blades are available in two types of industrial grade blades and gem quality blades. Diamond blades are used to cut hard materials such as bones and teeth. Gem-quality materials are primarily used for electron microscopy applications. A metal blade is used to slice sections of animal or plant tissue for light microscopy histology.
Different automated microtomes are used for different sample cutting. Laser microtomes are used in histopathology to cut any sample for histological examination and provide an advantage for accurate testing. The laser microtome is basically used for all samples >1 µm thick. A rotary microtome cuts samples 0.5 – 60 µm thick.
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The vibrating microtome is used to cut tough/soft, fresh/fixed samples in thicknesses of 10 µm (fixed) and 30 µm (fresh). Cryomicrotomes are used for frozen samples and are used in very specific thicknesses. Ultra microtomes are used for extremely thin cuts for analysis with special microscopes.
Based on geography, the automated microtome market is segmented into five major regions. North America, Asia Pacific, Latin America, Middle East & Africa, Europe. North America is projected to hold a large share of the global automated microtome market owing to rising per capita medical income and significant growth in spending on clinical laboratories. Asia Pacific is one of the fastest growing regions for the automated microtome market owing to increasing technological advancements and increasing awareness of various health aspects.
Competitive Outlook
Identified players in the global automated microtome market include Leica Biosystems Nussloch GmbH, Sakura Finetek Europe BV, Thermo Fisher Scientific Inc., Histo-Line Laboratories, Medite GmbH, Orion Medic, microTec Laborgeräte GmbH, Amos Scientific Pty Ltd, Diapath SpA . , SLEE Medical GmbH, SM Scientific Instrument Pvt. Ltd., MICROS Produktions-u.Handelsg.mbH, Boeckeler Instruments, Medimeas Instruments, etc.
The automated microtome market will grow owing to the growing number of histopathology laboratories, increasing awareness of digital pathology systems, and high growth of anatomical pathology laboratories in emerging economies. With the increasing use of technologically advanced methods, the adoption rate of equipment is high.
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