The DNA binding domain recognizes a unique hexameric sequence of DNA consisting of the nuclease domain of Fok I and a DNA cleavage domain. The fusion of a DNA binding domain and a DNA cleavage domain creates artificial restriction enzymes known as molecular scissors that cut the desired DNA. order. ZFNs are based on DNA repair machinery and are becoming a prominent tool in the field of genome editing.
Zinc finger nucleases are useful for a variety of biotechnology and life science applications. It is used to manipulate animals and plants for research purposes and is used in clinical trials of CD4+ human T cells for the treatment of AIDS. It is also used in the creation of disease models known as isogenic human disease models.
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The global zinc finger nuclease technology is segmented on the basis of application, end user, and region.
application
- cell line engineering
- animal genetics engineering
- plant genetic engineering
- Etc
end user
- biotechnology company
- pharmaceutical company
- Hospital laboratories and diagnostic laboratories
- Academic and research institutions
The global market for zinc finger nuclease technology is segmented by application type and end user. On the basis of application type, the zinc finger nuclease market is segmented into cell line engineering, animal genetic engineering, plant genetic engineering, and on the basis of end user, the market is divided into biotechnology industry, pharmaceutical companies, hospitals and diagnostic laboratories, academic and research institutions.
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As ZFN technology has technological advantages over other genome editing technologies, the high precision, specificity and efficacy of zinc finger technology predict the growth of the zinc finger technology market in the near future.
Based on regional presence, the global zinc finger nuclease technology market is segmented into five broad regions. North America, Latin America, Europe, Asia Pacific, Middle East and Africa. North America is estimated to be followed by European countries with a major share. Mainly, the US and European markets adopt advanced technologies earlier than developing countries due to the innate characteristics of advanced medical infrastructure, and they are geographically leading due to high prices of medicines/medical devices/technologies, and increasing pool of lifestyle-related diseases due to large-scale patients. is expected to keep.
Significant economic development will increase health care availability in the Asia-Pacific region, increase the number of research institutions, research institutes, increase investment in R&D, and penetration of global players in Asia will lead to increased demand for gene editing technologies such as zinc finger nucleases. demand is expected to increase. Advances in technology, diagnostic and therapeutic processes for research and development.
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Major players in zinc finger nuclease technology include Sigma-Aldrich Co. LLC., Sangamo Therapeutics, Inc. OriGene Technologies, Inc., Labomics, Thermo Fisher Scientific, and more. Sigma-Aldrich Co. LLC operates a life sciences business as part of Merck Inc. and has a presence in various geographies to meet the needs of its customers.
Sangamo Therapeutics, Inc. has developed a variety of gene editing technologies through therapeutic approaches. Many life science companies and large pharmaceutical companies are collaborating to develop and commercialize gene editing technology to introduce cutting-edge life science products.
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